Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection

Systemic absorption of Soframycin after subconjunctival injection.

Ocular penetration of cefazolin in humans and rabbits after subconjunctival injection.

We determined the clinical potential of cefazolin by assaying aqueous samples for levels of aqueous penetration of cefazolin in humans and rabbits after subconjunctival injection. Cefazolin is a broad spectrum antiotic that appears to penetrate aqueous humor in bactericidal concentrations after subconjunctival injection and may serve as a useful alternative in patients sensitive to other antibi...

Administering a subconjunctival injection

• Position the patient lying comfortably with his/her head supported on a pillow. • Reassure the patient that adequate anaesthetic drops will be instilled before the injection is given. • Instill anaesthetic drops at five-minute intervals over half an hour – a minimum of six drops. • Away from the patient’s view, draw up the prescribed medication using the 21G needle (Figure 1). • Change to the...

Regression of Iris Neovascularization after Subconjunctival Injection of Bevacizumab

To describe three cases of neovascular glaucoma (NVG) where iris or angle neovascularization regressed remarkably after subconjunctival bevacizumab injections used as the initial treatment before pan retinal photocoagulation (PRP) and/or filtering surgery. Three consecutive NVG patients whose intraocular pressure (IOP) was not controlled with maximal medication were offered an off-label subconj...

A Case of Herpetic Keratitis after Subconjunctival Triamcinolone Acetonide Injection

PURPOSE We report a case of herpetic epithelial keratitis that developed after subconjunctival triamcinolone acetonide injection (STI). METHODS A 65-year-old female with anterior uveitis and hypotony in her right eye was given a STI (2 mg/0.5 ml). After the injection, she developed redness and an ocular discharge. A clinical examination was performed and real-time polymerase chain reaction (P...